Search results for "Structural Dynamic"
showing 10 items of 19 documents
Structural Dynamics and Intentional Governance in Strategic Interorganizational Network Evolution: A Multilevel Approach
2016
This article aims to shed light on the drivers underlying the role and scope of intentional governance of the structural dynamics of whole interorganizational networks. Prior research has distinguished networks that are emergent from networks that are orchestrated. While empirical studies have shown situations in which the role and scope of intentional governance of whole interorganizational networks has changed in time, and there is a growing interest regarding the endogenous drivers of network dynamics, the dimensions that influence intentional governance of network structure dynamics and the way this is carried out remain still to be elucidated. In order to pinpoint these drivers, we le…
Visualizing a protein quake with time-resolved X-ray scattering at a free-electron laser
2014
We describe a method to measure ultrafast protein structural changes using time-resolved wide-angle X-ray scattering at an X-ray free-electron laser. We demonstrated this approach using multiphoton excitation of the Blastochloris viridis photosynthetic reaction center, observing an ultrafast global conformational change that arises within picoseconds and precedes the propagation of heat through the protein. This provides direct structural evidence for a 'protein quake': the hypothesis that proteins rapidly dissipate energy through quake-like structural motions. peerReviewed
The Monod-Wyman-Changeux allosteric model accounts for the quaternary transition dynamics in wild type and a recombinant mutant human hemoglobin
2012
International audience; The acknowledged success of the Monod-Wyman-Changeux (MWC) allosteric model stems from its efficacy in accounting for the functional behavior of many complex proteins starting with hemoglobin (the paradigmatic case) and extending to channels and receptors. The kinetic aspects of the allosteric model, however, have been often neglected, with the exception of hemoglobin and a few other proteins where conformational relaxations can be triggered by a short and intense laser pulse, and monitored by time-resolved optical spectroscopy. Only recently the application of time-resolved wide-angle X-ray scattering (TR-WAXS), a direct structurally sensitive technique, unveiled th…
Structural and Knowledge Dynamics in Inter-firm Complex Systems
2015
The paper aims to scrutinize the drivers of interfirm network structural dynamics and their influence on knowledge creation and diffusion over time. Interfirm knowledge networks are complex webs of linkages connecting a variety of idiosyncratic firms within and across industries. By serving as conduits through which information, knowledge and other resources flow and reputations are signaled (Poldony, 2001; Owen-Smith & Powell, 2004), they support cooperation in knowledge sharing and creation processes.
Determination of the oxygen transmissibility and permeability of hydrogel contact lenses
1999
To test the validity of the method of stacked hydrogel contact lenses to obtain the oxygen permeability and transmissibility coefficients of the lenses, the coefficients of one low hydration (38% water) and two high hydration (55 and 58% water) hydrogel contact lenses stacked one to five on an oxygen electrode were deter- mined. From the oxygen diffusion through the lenses, the current intensity in the stationary state was determined, and from this the "instrument" the oxygen transmis- sibility was obtained. The permeability coefficients of the lenses, corrected for edge effects, were obtained from the slope of the plot of the reciprocal of the transmissibility coefficients versus the lens …
Using synchrotrons and XFELs for time-resolved X-ray crystallography and solution scattering experiments on biomolecules
2015
International audience; Time-resolved structural information is key to understand the mechanism of biological processes, such as catalysis and signalling. Recent developments in X-ray sources as well as data collection and analysis methods are making routine time-resolved X-ray crystallography and solution scattering experiments a real possibility for structural biologists. Here we review the information that can be obtained from these techniques and discuss the considerations that must be taken into account when designing a time-resolved experiment.
Vibrations of a continuous web on elastic supports
2017
We consider an infinite, homogenous linearly elastic beam resting on a system of linearly elastic supports, as an idealized model for a paper web in the middle of a cylinder-based dryer section. We obtain closed-form analytical expressions for the eigenfrequencies and the eigenmodes. The frequencies increase as the support rigidity is increased. Each frequency is bounded from above by the solution with absolutely rigid supports, and from below by the solution in the limit of vanishing support rigidity. Thus in a real system, the natural frequencies will be lower than predicted by commonly used models with rigid supports. peerReviewed
Acute effects of shock-type vibration transmitted to the hand-arm system.
1984
The aim of the project was to find out whether shock-type vibration of hand-tools compared to non-impulsive vibration has stronger acute effects on the hand-arm system and therefore needs a stricter evaluation from the occupational health point of view in comparison with the requirements of the Draft International Standard ISO-DIS 5349. Under laboratory conditions, subjects were exposed to simulated vibration of hand-tools (grinder, chain saw, hammer-drill, pneumatic hammer, rivet hammer and nailer). The following evaluation criteria were used: biomechanical transmissibility of the hand-arm system (wrist, elbow joint, shoulder joint); muscle-activity (m. flexor carpi ulnaris, m. biceps, m. …
An Innovative Structural Dynamic Identification Procedure Combining Time Domain OMA Technique and GA
2022
In this paper an innovative and simple Operational Modal Analysis (OMA) method for structural dynamic identification is proposed. It combines the recently introduced Time Domain–Analytical Signal Method (TD–ASM) with the Genetic Algorithm (GA). Specifically, TD–ASM is firstly employed to estimate a subspace of candidate modal parameters, and then the GA is used to identify the structural parameters minimizing the fitness value returned by an appropriately introduced objective function. Notably, this method can be used to estimate structural parameters even for high damping ratios, and it also allows one to identify the Power Spectral Density (PSD) of the structural excitat…
Variable Friction Dampers (VFD) for a modulated mitigation of the seismic response of framed structures: Characteristics and design criteria
2022
In this paper a new approach for the energy dissipation is discussed based on the use of Variable Friction Dampers (VFDs). The VFD device is borrowed from braking systems mechanical engineering, able to modulate its capability of dissipation, providing a constant pure friction force coupled with an additional (variable) damping force with the increasing of the displacement. Resorting to a previous study, the characteristics and the efficiency of the “braking” system in terms of reduction of the displacements and the restoring forces is described for SDOF systems under seismic excitations and compared with the performances achievable by classic constant friction dampers (CFDs). Then, a desig…